WHAT IS HEALTHY LIFE?
What is Shift Work Disorder? Shift Work Disorder affects some people who work at night or frequently changes working shifts. In such cases, the schedules go against the body's natural circadian rhythm; many people have difficulty adjusting to a new sleep and wake pattern. The sleep interruption that results in turn cause difficulty in sleeping or excessive sleepiness. Disturbances to normal sleeping and waking patterns increase the risk of accidents and affect shift workers' health. In jobs where shift work cannot be avoided — including health care, the police force, or the military — drugs can potentially offer short-term benefits are used to prevent accidents. Modafinil, an orally administered wake-promoting agent, is indicated to improve wakefulness in adults with excessive sleepiness associated with obstructive sleep apnea (OSA), shift work disorder (SWD), and narcolepsy (In patients with OSA, Modafinil is recommended for use as an adjunct to standard therapies prescribed for the underlying airway obstruction. Modafinil was first approved in the United States in December 1998 for use in narcolepsy and subsequently in January 2004 for use in OSA and SWD. Excessive sleepiness is the inability to remain awake during situations when wakefulness and alertness are required or expected. It is a main presenting symptom of individuals seen in sleep clinics and affects a substantial proportion of the general population. In a survey conducted by the National Sleep Foundation, 37% of adults reported sleepiness severe enough to interfere with activities of daily living a few days or more each month; 16% of respondents indicated excessive sleepiness interfered with activities even more frequently. Causes of excessive sleepiness include inadequate restorative sleep due to shortened duration or fragmentation, circadian rhythm disturbance or misalignment, deregulations of intrinsic mechanisms responsible for promoting sleep and wakefulness, and the use of sedating medications (Excessive sleepiness is a prominent symptom of various disorders of sleep and wakefulness) and of other medical and psychiatric disorders.
Patient functioning was evaluated using the Functional Outcomes of Sleep Questionnaire (FOSQ), a self-administered, 30-item, validated instrument in a specific sleep disorder that measures the effect of excessive sleepiness on 5 domains of everyday living and quality of life. The FOSQ was administered at baseline and at weeks 4 and 12. The range of scores for each domain is 1 to 4; higher scores indicate greater function. FOSQ total scores were calculated by totaling the 5 sub-scale scores and, therefore, could range from 5 to 20. Health-related quality of life Night time sleep, daytime sleep, and caffeine consumption Patients completed daily diaries to record information on daytime sleep parameters (total time in bed, sleep duration, number of awakenings, and time awake after sleep onset) for each day after a night shift worked. Sleep efficiency was calculated as the percentage of sleep duration relative to the total time in bed. Patient diaries were also used to record caffeine consumption on a night shift worked and on the day after a night shift. Diaries were collected from patients at baseline and at weeks 4, 8, and 12. Use of the diary was introduced in a protocol amendment after the study started. Data from the 98 patients who provided analyzable diary data are summarized in the results section. Tolerability Adverse events were monitored throughout the study. Additional assessments included routine clinical laboratory tests (serum chemistry and hematol-ogy), vital signs (blood pressure and heart rate), electrocardiograms (ECGs), physical examinations, and concomitant medication usage. How Modafinil helps for Shift workers? Modafinil helps the workers with more concentration without feeling sleepy for a long period of time. Dopamine neurotransmitter is elevated in the brain which gives a sense of increased alertness and vigilance. Modafinil mechanism of action on dopamine can be compared to the feeling we consider as doing something good. The mechanism of action of this drug is connected to the nervous system of our brain. It affects the neurotransmitters to a certain extent to help achieve a wakefulness and alert state. Apart from wakefulness agent,Modafinil have enhances cognitive performance like attention span, concentration, improved memory, clear thought process and good mood. In addition, people suffering from ADHD, Schizophrenic have shown great improvement after taking Modafinil. You can get Modafinil online on various online medical stores but beware of the fake stores. It is really safe to order with Cash on Delivery option. As, it is the most trusted way for buying online products.
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